GC-MS ANALYST

Job Description:

GC–MS Analyst – Roles & Responsibilities

• Operate and maintain Gas Chromatography–Mass Spectrometry (GC-MS) systems for qualitative and quantitative analysis.

• Perform sample preparation, extraction, derivatization, and dilution as per approved methods.

• Develop, optimize, and validate GC-MS analytical methods in compliance with regulatory guidelines.

• Analyze chromatograms and interpret mass spectra using reference libraries (e.g., NIST).

• Conduct instrument calibration, system suitability tests, and performance verification.

• Identify and quantify unknown compounds, impurities, residual solvents, pesticides, or contaminants.

• Troubleshoot GC-MS issues related to columns, injectors, detectors, vacuum systems, and software.

• Ensure data integrity, accurate documentation, and timely reporting of results.

• Follow GLP, GMP, ISO, and regulatory standards during analysis and documentation.

• Prepare and review analytical reports, validation protocols, and SOPs.

• Perform routine preventive maintenance and coordinate instrument servicing.

• Handle chemical reagents safely and follow laboratory safety procedures.

• Support audits, inspections, and investigations related to analytical data.

• Collaborate with R&D, QA/QC, and production teams as required.

Key Skills Required

• GC-MS operation & troubleshooting

• Mass spectral interpretation

• Method development & validation

• Regulatory compliance (GMP/GLP/ISO)